• Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: a large prospective cohort study 

      Ritte, Rebecca; Lukanova, Annekatrin; Berrino, Franco; Dossus, Laure; Tjønneland, Anne; Olsen, Anja; Overvad, Thure F.; Overvad, Kim; Clavel-Chapelon, Françoise; Fournier, Agnes; Fagherazzi, Guy; Rohrmann, Sabine; Teucher, Birgit; Boeing, Heiner; Aleksandrova, Krasimira; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Sieri, Sabina; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Quiros, Jose R; Buckland, Genevieve; Sanchez, Maria-José; Amiano, Pilar; Chirlaque, María Dolores; Ardanaz, Eva; Sund, Malin; Lenner, Per; Bueno-de-Mesquita, Bas; van Gils, Carla H.; Peeters, Petra H.M.; Krum-Hansen, Sanda; Gram, Inger Torhild; Lund, Eiliv; Khaw, Kay-Tee; Wareham, Nick; Allen, Naomi E.; Key, Timothy J.; Romieu, Isabelle; Rinaldi, Sabina; Siddiq, Afshan; Cox, David; Riboli, Elio; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2012-05-14)
      Introduction: Associations of hormone-receptor positive breast cancer with excess adiposity are reasonably well characterized; however, uncertainty remains regarding the association of body mass index (BMI) with hormonereceptor negative malignancies, and possible interactions by hormone replacement therapy (HRT) use. Methods: Within the European EPIC cohort, Cox proportional hazards models were used ...
    • The association between adult attained height and sitting height with mortality in the European prospective investigation into cancer and nutrition (EPIC) 

      Sawada, Norie; Wark, Petra A.; Merritt, Melissa A.; Tsugane, Shoichiro; Ward, Heather A.; Rinaldi, Sabina; Weiderpass, Elisabete; Dartois, Laureen; His, Mathilde; Boutron-Ruault, Marie-Christine; Turzanski-Fortner, Renée; Kaaks, Rudolf; Overvad, Kim; Redondo, María-Luisa; Travier, Noemie; Molina-Portillo, Elena; Dorronsoro, Miren; Cirera, Lluis; Ardanaz, Eva; Perez-Cornago, Aurora; Trichopoulou, Antonia; Lagiou, Pagona; Valanou, Elissavet; Masala, Giovanna; Pala, Valeria; Peeters, Petra H.M.; van der Schouw, Yvonne T.; Melander, Olle; Manjer, Jonas; da Silva, Marisa Eleonor; Skeie, Guri; Tjønneland, Anne; Olsen, Anja; Gunter, Mark J.; Riboli, Elio; Cross, Amanda J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-03)
      Adult height and sitting height may reflect genetic and environmental factors, including early life nutrition, physical and social environments. Previous studies have reported divergent associations for height and chronic disease mortality, with positive associations observed for cancer mortality but inverse associations for circulatory disease mortality. Sitting height might be more strongly ...
    • The association of education with body mass index and waist circumference in the EPIC-PANACEA study 

      Hermann, Silke; Rohrmann, Sabine; Linseisen, Jakob; May, Anne M.; Kunst, Anton; Besson, Herve; Romaguera, Dora; Travier, Noemie; Tormo, Maria-José; Molina, Esther; Dorronsoro, Miren; Barricarte, Aurelio; Rodriguez, Laudina; Crowe, Francesca L.; Khaw, Kay-Tee; Wareham, Nicholas J.; van Boeckel, Petra G.A.; Bueno-de-Mesquita, H. Bas; Overvad, Kim; Jakobsen, Marianne Uhre; Tjønneland, Anne; Halkjær, Jytte; Agnoli, Claudia; Mattiello, Amalia; Tumino, Rosario; Masala, Giovanna; Vineis, Paolo; Naska, Androniki; Orfanos, Philippos; Trichopoulou, Antonia; Kaaks, Rudolf; Bergmann, Manuela M.; Steffen, Annika; Van Guelpen, Bethany; Johansson, Ingegerd; Borgquist, Signe; Manjer, Jonas; Braaten, Tonje; Fagherazzi, Guy; Clavel-Chapelon, Françoise; Mouw, Traci; Norat, Teresa; Riboli, Elio; Rinaldi, Sabina; Slimani, Nadia; Peeters, Petra H.M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      To examine the association of education with body mass index (BMI) and waist circumference (WC) in the European Prospective Investigation into Cancer and Nutrition (EPIC). This study included 141,230 male and 336,637 female EPIC-participants, who were recruited between 1992 and 2000. Education, which was assessed by questionnaire, was classified into four categories; BMI and WC, measured by trained ...
    • Combined Impact of Lifestyle Factors on Prospective Change in Body Weight and Waist Circumference in Participants of the EPIC-PANACEA Study 

      May, Anne M.; Romaguera, Dora; Travier, Noémie; Ekelund, Ulf; Bergmann, Manuela M.; Kaaks, Rudolf; Teucher, Birgit; Steffen, Annika; Boeing, Heiner; Halkjaer, Jytte; Tjonneland, Anne; Jakobsen, Marianne Uhre; Overvad, Kim; Dartois, Laureen; Fagherazzi, Guy; Boutron-Ruault, Marie-Christine; Quirós, J. Ramón; Agudo, Antonio; Gonzalez, Carlos; Sanchez, Maria-José; Amiano, Pilar; Huerta, José-Maria; Ardanaz, Eva; Wareham, Nicholas J.; Crowe, Francesca L.; Naska, Androniki; Orfanos, Philippos; Trichopoulou, Antonia; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; Verschuren, Monique; Drake, Isabel; Sonestedt, Emily; Braaten, Tonje; Rinaldi, Sabina; Romieu, Isabelle; Slimani, Nadia; Norat, Teresa; Riboli, Eilo; Peeters, Petra H.M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      The evidence that individual dietary and lifestyle factors influence a person’s weight and waist circumference is well established; however their combined impact is less well documented. Therefore, we investigated the combined effect of physical activity, nutrition and smoking status on prospective gain in body weight and waist circumference. We used data of the prospective EPIC-PANACEA study. ...
    • A comprehensive analysis of the androgen receptor gene and risk of breast cancer. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3) 

      Cox, David G.; Lund, Eiliv; Blanché, Hélène; Pearce, Celeste L.; Calle, Eugenia E.; Colditz, Graham A.; Pike, Malcolm C.; Albanes, Demetrius; Allen, Naomi E.; Amiano, Pilar; Berglund, Göran; Boeing, Heiner; Buring, Julie; Burtt, Noel; Canzian, Federico; Chanock, Stephen; Flavel-Chapelon, Françoise; Feigelson, Heather Spencer; Freedman, Matthew; Haiman, Christopher A.; Hankinson, Susan E.; Henderson, Brian E.; Hoover, Robert; Hunter, David J.; Kaaks, Rudolf; Kolonel, Laurence; Kraft, Peter; LeMarchand, Loic; Palli, Domenico; Peeters, Petra H.M.; Riboli, Elio; Stram, Daniel O.; Thun, Michael; Tjönneland, Anne; Trichopoulos, Dimitrios; Yeager, Meredith (Journal article; Tidsskriftartikkel; Peer reviewed, 2006-09-20)
      Introduction Androgens have been hypothesised to influence risk of breast cancer through several possible mechanisms, including their conversion to estradiol or their binding to the oestrogen receptor and/or androgen receptor (AR) in the breast. Here, we report on the results of a large and comprehensive study of the association between genetic variation in the AR gene and risk of breast cancer ...
    • Consumption of dairy products and colorectal cancer in the European prospective investigation into cancer and nutrition (EPIC) 

      Murphy, Neil; Norat, Teresa; Ferrari, Pietro; Jenab, Mazda; Bueno-de-Mesquita, Bas; Skeie, Guri; Olsen, Anja; Tjønneland, Anne; Dahm, Christina C.; Overvad, Kim; Boutron-Ruault, Marie Christine; Clavel-Chapelon, Françoise; Nailler, Laura; Kaaks, Rudolf; Teucher, Birgit; Boeing, Heiner; Bergmann, Manuela M.; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Pala, Valeria; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Peeters, Petra H.M.; Dik, Vincent K.; Weiderpass, Elisabete; Lund, Eiliv; Garcia, José Ramon Quiros; Zamora-Ros, Raul; Pérez, Maria José Sánches; Dorronsoro, Miren; Navarro, Carmen; Ardanaz, Eva; Manjer, Jonas; Almquist, Martin; Johansson, Ingegerd; Palmqvist, Richard; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Crowe, Francesca L.; Fedirko, Veronika; Gunter, Mark J.; Riboli, Elio (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Prospective studies have consistently reported lower colorectal cancer risks associated with higher intakes of total dairy products, total milk and dietary calcium. However, less is known about whether the inverse associations vary for individual dairy products with differing fat contents. Materials and Methods: In the European Prospective Investigation into Cancer and Nutrition (EPIC), ...
    • Determinants of non- response to a second assessment of lifestyle factors and body weight in the EPIC-PANACEA study 

      May, Anne M.; Adema, Lotte E.; Romaguera, Dora; Vergnaud, Anne-Claire; Agudo, Antonio; Ekelund, Ulf; Steffen, Annika; Orfanos, Philippos; Slimani, Nadia; Rinaldi, Sabina; Mouw, Traci; Rohrmann, Sabine; Hermann, Silke; Boeing, Heiner; Bergmann, Manuela M.; Jakobsen, Marianne Uhre; Overvad, Kim; Wareham, Nicholas J.; Gonzalez, Carlos; Tjonneland, Anne; Halkjaer, Jytte; Key, Timothy J.; Spencer, Elizabeth A.; Hellström, Veronica; Manjer, Jonas; Hedblad, Bo; Lund, Eiliv; Braaten, Tonje; Clavel-Chapelon, Françoise; Boutron-Ruault, Marie Christine; Rodriguez, Laudina; Sanchez, Maria Jose; Dorronsoro, Miren; Barricarte, Aurelio; Huerta, Jose Maria; Naska, Androniki; Trichopoulou, Antonia; Palli, Domenico; Pala, Valeria; Norat, Teresa; Mattiello, Amalia; Tumino, Rosario; van der Daphne, A.; Bueno-de-Mesquita, H. Bas; Riboli, Elio; Peeters, Petra H.M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      This paper discusses whether baseline demographic, socio-economic, health variables, length of follow-up and method of contacting the participants predict non-response to the invitation for a second assessment of lifestyle factors and body weight in the European multi-center EPIC-PANACEA study. Over 500.000 participants from several centers in ten European countries recruited between 1992 and 2000 ...
    • DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility 

      Ambatipudi, Srikant; Horvath, Steve; Perrier, Flavie; Cuenin, Cyrille; Hernandez-Vargas, Hector; Le Calvez-Kelm, Florence; Durand, Geoffroy; Byrnes, Graham; Ferrari, Pietro; Bouaoun, Liacine; Sklias, Athena; Chajès, Véronique; Overvad, Kim; Severi, Gianluca; Baglietto, Laura; Clavel-Chapelon, Françoise; Kaaks, Rudolf; Barrdahl, Myrto; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Naska, Androniki; Masala, Giovanna; Agnoli, Claudia; Polidoro, Silvia; Tumino, Rosario; Panico, Salvatore; Dollé, Martijn; Peeters, Petra H.M.; Onland-Moret, N. Charlotte; Sandanger, Torkjel M; Nøst, Therese Haugdahl; Weiderpass, Elisabete; Quirós, José Ramón; Agudo, Antonio; Rodriguez-Barranco, Miguel; Huerta Castaño, José María; Barricarte, Aurelio; Fernández, Ander Matheu; Travis, Ruth C.; Vineis, Paolo; Muller, David C.; Riboli, Elio; Gunter, Marc; Romieu, Isabelle; Herceg, Zdenko (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-28)
      Aim of the study: A vast majority of human malignancies are associated with ageing, and age is a strong predictor of cancer risk. Recently, DNA methylation-based marker of ageing, known as ‘epigenetic clock’, has been linked with cancer risk factors. This study aimed to evaluate whether the epigenetic clock is associated with breast cancer risk susceptibility and to identify potential epigenetics-based ...
    • Fruit and vegetable consumption in relation to hepatocellular carcinoma in a multi-centre, European cohort study 

      Bamia, Christina; Lagiou, Pagona; Jenab, Mazda; Aleksandrova, Krasimira; Fedirko, Veronika; Trichopoulos, Dimitrios; Overvad, Kim; Tjønneland, Anne; Olsen, Anja; Clavel-Chapelon, Françoise; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina; Katzke, Verena A.; Kühn, Tilman; Boeing, Heiner; Nöthlings, Ute; Palli, Domenico; Sieri, Sabina; Panico, Salvatore; Tumino, Rosaria; Naccarati, Allessio; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.M.; Weiderpass, Elisabete; Skeie, Guri; Quirós, José Ramón; Agudo, Antonio; Chirlaque, María-Dolores; Sánchez, María-José; Ardanaz, Eva; Dorronsoro, Miren; Ericson, Ulrika; Nilsson, Lena Maria; Wennberg, Maria; Khaw, Kay-Tee; Wareham, Nicholas J.; Key, Timothy J.; Travis, Ruth C.; Ferrari, Pietro; Stepien, Magdalena; Duarte-Salles, Talita; Norat, Teresa; Murphy, Neil; Riboli, Eilo; Trichopoulou, Antonia (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-05)
      Background: Vegetable and/or fruit intakes in association with hepatocellular carcinoma (HCC) risk have been investigated in case–control studies conducted in specific European countries and cohort studies conducted in Asia, with inconclusive results. No multi-centre European cohort has investigated the indicated associations. Methods: In 486 799 men/women from the European Prospective Investigation ...
    • Heterogeneity of colorectal cancer risk factors by anatomical subsite in 10 European countries: A multinational cohort study 

      Murphy, Neil; Ward, Heather A.; Jenab, Mazda; Rothwell, Joseph A.; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Kvaskoff, Marina; Kaaks, Rudolf; Kühn, Tilman; Boeing, Heiner; Aleksandrova, Krasimira; Weiderpass, Elisabete; Skeie, Guri; Borch, Kristin Benjaminsen; Tjønneland, Anne; Kyrø, Cecilie; Overvad, Kim; Dahm, Christina C.; Jakszyn, Paula; Sánchez, María-José; Gil, Leire; Huerta, José María; Barricarte, Aurelio; Quirós, José Ramón; Khaw, Kay-Tee; Wareham, Nick; Bradbury, Kathryn E.; Trichopoulou, Antonia; La Vecchia, Carlo; Karakatsani, Anna; Palli, Domenico; Grioni, Sara; Tumino, Rosario; Fasanelli, Francesca; Panico, Salvatore; Bueno-de-Mesquita, Hendrik Bastiaan; Peeters, Petra H.M.; Gylling, Björn; Myte, Robin; Jirström, Karin; Berntsson, Jonna; Xue, Xiaonan; Riboli, Elio; Cross, Amanda J.; Gunter, Mark J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-26)
      <i>Background & Aims</i> - Colorectal cancer located at different anatomical subsites may have distinct etiologies and risk factors. Previous studies that have examined this hypothesis have yielded inconsistent results, possibly because most studies have been of insufficient size to identify heterogeneous associations with precision.<p><p> <i>Methods</i> - In the European Prospective Investigation ...
    • Macronutrient composition of the diet and prospective weight change in participants of the EPIC-PANACEA study 

      Vergnaud, Anne-Claire; Norat, Teresa; Mouw, Traci; Romaguera, Dora; May, Anne M.; Bueno-de-Mesquita, H. Bas; van der A, Daphne; Agudo, Antonio; Wareham, Nicholas; Khaw, Kay-Tee; Romieu, Isabelle; Freisling, Heinz; Slimani, Nadia; Perquier, Florence; Boutron-Ruault, Marie-Christine; Clavel-Chapelon, Françoise; Palli, Domenico; Berrino, Franco; Mattiello, Amalia; Tumino, Rosario; Ricceri, Fulvio; Rodriguez, Laudina; Molina-Montes, Esther; Amiano, Pilar; Barricarte, Aurelio; Chirlaque, Maria-Dolores; Crowe, Francesca L.; Orfanos, Philippos; Naska, Androniki; Trichopoulou, Antonia; Teucher, Birgit; Kaaks, Rudolf; Boeing, Heiner; Buijsse, Brian; Johansson, Ingegerd; Hallmans, Göran; Drake, Isabel; Sonestedt, Emily; Jakobsen, Marianne Uhre; Overvad, Kim; Tjønneland, Anne; Halkjær, Jytte; Skeie, Guri; Braaten, Tonje; Lund, Eiliv; Riboli, Eilo; Peeters, Petra H.M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: The effect of the macronutrient composition of the usual diet on long term weight maintenance remains controversial. Methods: 373,803 subjects aged 25–70 years were recruited in 10 European countries (1992–2000) in the PANACEA project of the EPIC cohort. Diet was assessed at baseline using country-specific validated questionnaires and weight and height were measured at baseline and ...
    • Measured adiposity in relation to head and neck cancer risk in the European prospective investigation into cancer and nutrition. 

      Ward, Heather A.; Wark, Petra A.; Muller, David C.; Steffen, Annika; Johansson, Mattias; Norat, Teresa; Gunter, Marc J.; Overvad, Kim; Dahm, Christina C; Halkjær, Jytte; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Fagherazzi, Guy; Mesrine, Sylvie; Brennan, Paul; Freisling, Heinz; Li, Kuanrong; Kaaks, Rudolf; Trichopoulou, Antonia; Lagiou, Pagona; Panico, Salavatore; Grioni, Sara; Tumino, Rosario; Vineis, Paolo; Palli, Domenico; Peeters, Petra H.M.; Bueno-De-Mesquita, Hendrik Bastiaan; Weiderpass, Elisabete; Agudo, Antonio; Quirós, José Ramón; Larrañaga, Nerea; Ardanaz, Eva; Huerta, José María; Sánchez, María-José; Laurell, Göran; Johansson, Ingegerd; Westin, Ulla; Wallström, Peter; Bradbury, Kathryn E.; Wareham, Nicholas J.; Khaw, Kay-Tee; Pearson, Clare; Boeing, Heiner; Riboli, Elio (Journal article; Tidsskriftartikkel, 2017-06)
      <b>Background</b>: Emerging evidence from cohort studies indicates that adiposity is associated with greater incidence of head and neck cancer. However, most studies have used self-reported anthropometry which is prone to error.<br><b>Methods</b>: Among 363,094 participants in the European Prospective Investigation into Cancer and Nutrition study (EPIC) with measured anthropometry, there were 837 ...
    • Meat consumption and mortality - results from the European Prospective Investigation into Cancer and Nutrition 

      Rohrmann, Sabine; Overvad, Kim; Bueno-de-Mesquita, H. Bas; Jakobsen, Marianne Uhre; Egeberg, Rikke; Tjønneland, Anne; Nailler, Laura; Boutron-Ruault, Marie Christine; Clavel-Chapelon, Françoise; Krogh, Vittorio; Palli, Domenico; Panico, Salvatore; Tumino, Rosario; Ricceri, Fulvio; Bergmann, Manuela M.; Boeing, Heiner; Li, Kuanrong; Kaaks, Rudolf; Khaw, Kay Tee; Wareham, Nicholas J.; Crowe, Francesca L.; Key, Timothy J.; Naska, Androniki; Trichopoulou, Antonia; Trichopoulos, Dimitrios; Leenders, Max; Peeters, Petra H.M.; Engeset, Dagrun; Parr, Christine Louise; Skeie, Guri; Jakszyn, Paula; Sánchez, Maria-José; Huerta, Jose Maria; Redondo, ML; Barricarte, Aurelio; Amiano, Pilar; Drake, Isabel; Sonestedt, Emily; Hallmans, Göran; Johansson, Ingegerd; Fedirko, Veronika; Romieux, Isabelle; Ferrari, Pietro; Norat, Teresa; Vergnaud, Anne-Claire; Riboli, Elio; Linseisen, Jakob (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Recently, some US cohorts have shown a moderate association between red and processed meat consumption and mortality supporting the results of previous studies among vegetarians. The aim of this study was to examine the association of red meat, processed meat, and poultry consumption with the risk of early death in the European Prospective Investigation into Cancer and Nutrition ...
    • Multiple miscarriages are associated with the risk of ovarian cancer: results from the European prospective investigation into cancer and nutrition 

      Braem, Marieke G.M.; Onland-Moret, N. Charlotte; Schouten, Leo J; Kruitwagen, Roy F.P.M.; Lukanova, Annekatrin; Allen, Naomi E.; Wark, Petra A.; Tjønneland, Anne; Hansen, Louise; Braüner, Christina Marie; Overvad, Kim; Clavel-Chapelon, Françoise; Chabbert-Buffet, Nathalie; Teucher, Birgit; Floegel, Anna; Boeing, Heiner; Trichopoulou, Antonia; Adarakis, George; Plada, Maria; Rinaldi, Sabina; Fedirko, Veronika; Romieu, Isabelle; Pala, Valeria; Galasso, Rocco; Sacerdote, Carlotta; Palli, Domenico; Tumino, Rosario; Bueno-De-Mesquita, H. Bas; Gram, Inger Torhild; Gavrilyuk, Oxana; Lund, Eiliv; Sanchez, Maria-José; Bonet, Catalina; Chirlaque, María Dolores; Larranaga, Nerea; Gurrea, Aurelio Barricarte; Quirós, José R.; Idahl, Annika; Ohlson, Nina; Lundin, Eva; Jirström, Karin; Butt, Salma; Tsilidis, Konstantinos K.; Khaw, Kay-Tee; Wareham, Nick; Riboli, Elio; Kaaks, Rudolf; Peeters, Petra H.M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      While the risk of ovarian cancer clearly reduces with each full-term pregnancy, the effect of incomplete pregnancies is unclear. We investigated whether incomplete pregnancies (miscarriages and induced abortions) are associated with risk of epithelial ovarian cancer. This observational study was carried out in female participants of the European Prospective Investigation into Cancer and Nutrition ...
    • Osteoprotegerin and breast cancer risk by hormone receptor subtype: A nested case-control study in the EPIC cohort 

      Fortner, Renée T.; Sarink, Danja; Schock, Helena; Johnson, Theron; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Affret, Aurelie; His, Mathilde; Boutron-Ruault, Marie-Christine; Boeing, Heiner; Trichopoulou, Antonia; Naska, Androniki; Orfanos, Philippos; Palli, Domenico; Sieri, Sabina; Mattiello, Amalia; Tumino, Rosario; Ricceri, Fulvio; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.M.; van Gils, Carla H.; Weiderpass, Elisabete; Lund, Eiliv; Quirós, J. Ramón; Agudo, Antonio; Sánchez, María-José; Chirlaque, María-Dolores; Ardanaz, Eva; Dorronsoro, Miren; Key, Tim; Khaw, Kay-Tee; Rinaldi, Sabina; Dossus, Laure; Gunter, Marc; Merritt, Melissa A.; Riboli, Elio; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-08)
      Background:<br>Circulating osteoprotegerin (OPG), a member of the receptor activator of nuclear factor kappa-B (RANK) axis, may influence breast cancer risk via its role as the decoy receptor for both the RANK ligand (RANKL) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Circulating OPG and breast cancer risk has been examined in only one prior study.<br>Methods:<br>A case-control ...
    • Plasma elaidic acid level as biomarker of industrial trans fatty acids and risk of weight change: Report from the EPIC study 

      Chajès, Véronique; Biessy, Carine; Ferrari, Pietro; Romieu, Isabelle; Freisling, Heinz; Huybrechts, Inge; Scalbert, Augustin; Bueno-de-Mesquita, H. Bas; Romaguera, Dora; Gunter, Mark J.; Vineis, Paolo; Hansen, Camilla Plambeck; Jakobsen, Marianne Uhre; Clavel-Chapelon, Françoise; Fagherazzi, Guy; Boutron-Ruault, Marie-Christine; Katzke, Verana; Neamat-Allah, Jasmine; Boeing, Heiner; Bachlechner, Ursula; Trichopoulou, Antonia; Naska, Androniki; Orfanos, Philippos; Pala, Valeria; Masala, Giovanna; Mattiello, Amalia; Skeie, Guri; Weiderpass, Elisabete; Agudo, Antonio; Huerta, José María; Sánchez, Mariá-José; Dorronsoro, Miren; Quirós, José Ramón; Johansson, Ingegerd; Winkvist, Anna; Sonested, Emily; Key, Timothy J.; Khaw, Kay-Tee; Wareham, Nicholas J.; Peeters, Petra H.M.; Slimani, Nadia (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-12)
      Background Few epidemiological studies have examined the association between dietary trans fatty acids and weight gain, and the evidence remains inconsistent. The main objective of the study was to investigate the prospective association between biomarker of industrial trans fatty acids and change in weight within the large study European Prospective Investigation into Cancer and Nutrition ...
    • Pre-diagnostic meat and fibre intakes in relation to colorectal cancer survival in the European Prospective Investigation into Cancer and Nutrition 

      Ward, Heather A.; Norat, Teresa; Overvad, Kim; Dahm, Christina C.; Bueno-de-Mesquita, H. Bas; Jenab, Mazda; Fedirko, Veronika; van Duijnhoven, Fränzel J.B.; Skeie, Guri; Romaguera-Bosch, Dora; Tjønneland, Anne; Olsen, Anja; Carbonnel, Franck; Affret, Aurélie; Boutron-Ruault, Marie-Christine; Katzke, Verena; Kühn, Tilman; Aleksandrova, Krassimira; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Bamia, Christina; Palli, Domenico; Sieri, Sabina; Tumino, Rosario; Naccarati, Alessio; Mattiello, Amalia; Peeters, Petra H.M.; Weiderpass, Elisabete; Åsli, Lene Angell; Jakszyn, Paula; Ramõn Quirõs, Jose; Sánchez, María-José; Dorronsoro, Miren; Huerta, José María; Barricarte, Aurelio; Jirström, Karin; Ericson, Ulrika; Johansson, Ingegerd; Gylling, Björn; Bradbury, Kathryn E.; Khaw, Kay-Tee; Wareham, Nicholas J.; Stepien, Magdalena; Freisling, Heinz; Murphy, Neil; Cross, Amanda J.; Riboli, Elio (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-19)
    • Receptor activator of nuclear factor kB ligand, osteoprotegerin, and risk of death following a breast cancer diagnosis: results from the EPIC cohort 

      Sarink, Danja; Schock, Helena; Johnson, Theron; Chang-Claude, Jenny; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Arveux, Patrick; Fournier, Agnès; Kvaskoff, Marina; Boeing, Heiner; Karakatsani, Anna; Trichopoulou, Antonia; La Vecchia, Carlo; Masala, Giovanna; Agnoli, Claudia; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; van Gils, Carla H.; Peeters, Petra H.M.; Weiderpass, Elisabete; Agudo, Antonio; Rodríguez-Barranco, Miguel; Huerta, José María; Ardanaz, Eva; Gil, Leire; Kaw, Kay Tee; Schmidt, Julie A.; Dossus, Laure; His, Mathilde; Aune, Dagfinn; Riboli, Elio; Kaaks, Rudolf; Fortner, Renée T. (Journal article; Peer reviewed, 2018-10-22)
      <b>Background</b><br> Receptor activator of nuclear factor kappa-B (RANK)-signaling is involved in tumor growth and spread in experimental models. Binding of RANK ligand (RANKL) to RANK activates signaling, which is inhibited by osteoprotegerin (OPG). We have previously shown that circulating soluble RANKL (sRANKL) and OPG are associated with breast cancer risk. Here we extend these findings to ...
    • Sources of pre-analytical variations in yield of DNA extracted from blood samples: analysis of 50,000 DNA samples in EPIC 

      Caboux, Elodie; Lallemand, Christophe; Ferro, Gilles; Hemon, Bertrand; Mendy, Maimuna; Biessy, Carine; Sims, Matt; Wareham, Nicholas; Britten, Abigail; Boland, Anne; Hutchinson, Amy; Siddiq, Afshan; Vineis, Paolo; Riboli, Elio; Romieu, Isabelle; Rinaldi, Sabina; Gunter, Mark J.; Peeters, Petra H.M.; van der Schouw, Yvonne T.; Travis, Ruth C.; Bueno-De-Mesquita, H. Bas; Canzian, Federico; Sanchez, Maria-José; Skeie, Guri; Olsen, Karina Standahl; Lund, Eiliv; Bilbao, Roberto; Sala, Núria; Barricarte, Aurelio; Palli, Domenico; Navarro, Carmen; Panico, Salvatore; Redondo, Maria Luisa; Polidoro, Silvia; Dossus, Laure; Boutron-Ruault, Marie-Christine; Clavel-Chapelon, Françoise; Trichopoulou, Antonia; Trichopoulos, Dimitrios; Lagiou, Pagona; Boeing, Heiner; Fisher, Eva; Tumino, Rosario; Agnoli, Claudia; Hainaut, Pierre (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      The European Prospective Investigation into Cancer and nutrition (EPIC) is a long-term, multi-centric prospective study in Europe investigating the relationships between cancer and nutrition. This study has served as a basis for a number of Genome-Wide Association Studies (GWAS) and other types of genetic analyses. Over a period of 5 years, 52,256 EPIC DNA samples have been extracted using an automated ...